Throughout the ages, the cannabis plant provided our ancestors with a source of textiles, food and herbal medicine. The evidence of the historical use of the cannabis plants, marijuana, and hemp, has been documented across the continents and cultures worldwide. Cannabis use is deeply rooted in the traditions of herbal medicine. Centuries passed before anyone could understand why cannabis had the potential to alleviate so many seemingly unrelated symptoms.
Over time, marijuana use fell out of favor. Many states started restricting marijuana use beginning in 1906; prohibition began in the 1920s. While the original goal may have been curtailing marijuana use, once it was discovered that hemp was also a variety of cannabis sativa, the two plants were both banned, even though hemp was still considered a valued resource.
In the 1980s, our government allocated tens of millions of dollars to prove that marijuana use caused brain damage. When these suspicions were proven false, the Reagan administration funded several studies leading scientists to some pretty amazing discoveries.
While investigating the effects of THC (tetrahydrocannabinol), the cannabinoid responsible for marijuana’s psychoactive properties, researchers discovered a fascinating system of neurotransmitters and receptors that allow your body and brain to communicate.
While the study of this system is still in its infancy, science has discovered what this system is, what this system does and how it potentially interacts with cannabidiol (CBD). This recently discovered communication system is named for the plant that led researchers down the path to their discoveries. It is called the endocannabinoid system.
You have endocannabinoid receptors throughout your body. These receptors need to be activated by neurotransmitters. This continuous communication network is responsible for the maintenance and function of almost every system in your body, including:
Now that you know what your endocannabinoid system does, you may need to know how it works before you can see the potential benefits of supplementing your body’s communication system. The receptors throughout your body need a messenger (neurotransmitter) to unlock the receptor and generate a response. There are two types of messengers.
Endocannabinoids are the neurotransmitters made by your body. The two main endocannabinoids are anandamide and 2-AG (2-arachidonoyl glycerol). The highest concentration of 2- AG is needed in the brain. Anandamide is found in higher concentrations throughout the rest of your body. Your body makes these two lipids as needed and they are broken down quickly.
Exogenous cannabinoids are from a source outside of your body. If you guess we were going to say cannabis, you are right. The important distinction we need to make at this point is that the exogenous cannabinoids, CBD (cannabidiol), extracted from the cannabis plant marijuana also contains high amounts of THC. The cannabidiol from the cannabis plant hemp provides the same potential benefits to your endocannabinoid system, without high levels of THC, without any risk of impairment or intoxication.
Now that you are a little more familiar with the endocannabinoid messengers, it may be beneficial to know a bit more about the endocannabinoid receptors. There are also two.
Although CB1 receptors can be found throughout your body, they are most concentrated in your brain and spinal cord. Their function is determined by their location. For example, the CB1 receptors in your amygdala influence your emotional responses and memory, while the CB1 receptors that regulate your appetite are in your hypothalamus.
CB2 receptors are most concentrated within your immune system and your peripheral nervous system. CB2 receptors control your immune functions and inflammation. Inflammation is now believed to be the source of many health conditions including heart disease.
Researchers believe that the purpose of your endocannabinoid system is to regulate and stabilize the processes necessary for survival (homeostasis). Ideally, this system would stay balanced, and communication would continue uninterrupted.
Unfortunately, when under physical strain or emotional stress, your endocannabinoid system may need more endocannabinoids than your body can produce. Without cannabinoids, the communication system is impaired, and the system can fall out of balance. Some researchers are leaning toward the belief that many conditions may be caused by endocannabinoid deficiencies.
That’s where cannabidiol (CBD) comes into the picture. The exogenous cannabinoids in cannabis mimic the effects of the endocannabinoids made by your body, but the effects are stronger and longer lasting. Some of the many conditions that could benefit from CBD supplements include:
You may notice that the potential benefits of CBD coincide with the functions in your body regulated by your endocannabinoid system. While our ancestors may not have understood why cannabis was so versatile, it appears we have the answer.
Decades ago, hemp was shunned simply for being a cannabis plant. Now the distinction has been made between the cannabinoid sources. Since the CBD extracted from hemp contains only a trace amount of THC, (<0.3 percent), it cannot cause any psychoactive effects and is no longer regulated by the Drug Enforcement Administration (DEA).
Thanks to the Agricultural Act of 2014 (The US Farm Bill), it is once again legal to grow industrial hemp in 19 states for pilot programs and research, will more states hoping to join in.
One of the most prevalent ways to reap the potential rewards of CBD is by using a CBD tincture. When using a tincture, you have several options. Some studies suggest that using the tincture sublingually yields the best results.
To use a tincture in this manner, you simply hold the CBD oil under your tongue for several seconds before swallowing. This allows for some of the cannabinoids in the CBD oil to enter your bloodstream before entering your digestive tract.
Pure CBD extract has a flavor that is often described as earthy, grassy or nutty. It is understandable if holding a plant-based oil under your tongue does not appeal to you. There are many who prefer to mix their CBD oil with their favorite beverage or blend their CBD with yogurt, ice cream or a fruit smoothie.
Many CBD enthusiasts immediately enjoy the flavor of their CBD products, while others develop a taste along the way. For those who prefer to avoid the flavor of their CBD supplements, or prefer the convenience, there is also the option of swallowing your CBD in a capsule.
When selecting a CBD capsule, you are investing in a product that supplies all the potential benefits of CBD supplementation in a form that is much more familiar. Even those who typically use CBD tinctures often keep a supply of capsules on hand for times when convenience matters. There are many advantages, including:
CBD, in any form, is not a medication. It is not a cure for any disorder. CBD is a dietary supplement with the potential to alleviate symptoms that could be caused by an imbalance within your endocannabinoid system.
You need to know that the list of potential benefits is based on laboratory findings, animal research and the testimony of those who find CBD supplements potentially beneficial to their health and well- being. No medical claims are made at this time.
When searching for a CBD oil or capsule, keep in mind that it is best to use CBD sourced from non-GMO, pesticide-free hemp. While insecticides, herbicides, and chemical fertilizers are often used in farming to promote plant health an increased crop yields, hemp grown for consumption should always be free from these types of contaminants.
That’s because hemp absorbs and retains these compounds. In fact, hemp shows a remarkable ability to remove contaminants from the soil and clear toxins.
Download The Ultimate User Guide to learn more about CBD supplements and the importance of selecting non-GMO, pesticide-free CBD products. We encourage you to absorb all the information you can about your endocannabinoid system and supplementing this system with natural hemp-based products. Whether you prefer capsules, tinctures or vape products, visit CBDistillery to learn more about the potential benefits of CBD and how CBD supplements may benefit you.
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Cannabidiol, or CBD is a non-psychoactive, naturally occurring compound in cannabis plants which has been steadily gaining a lot of attention due to its many potential health and wellness benefits. This essential oil is extracted from the hemp and marijuana plants which are both members of the cannabis family. CBD oil has the potential to support the vital communication network responsible for regulating many essential functions throughout your body.
Although there is a multitude of CBD products available on the market, CBD oil tends to be the most popular product among users. CBD oil is beloved for its easy-to-use formula and high bioavailability. Touted for its many effects on the body and mind, people use CBD oil for a variety of reasons — most often to increase general health and wellbeing.
Because CBD is extracted from cannabis, it is understandable that some have concerns about using a CBD oil. If you are interested in learning more about CBD oil, this beginner’s guide will answer all of your questions. In this guide, we’ll go over the history, dosage, effects, and extraction process of CBD oil. We’ll also cover common confusions like the difference between two cannabis plants (hemp and marijuana), and the effects of CBD versus THC.
Cannabis sativa is thought to be one of the earliest crops planted by man, dating back to the beginning of the agricultural revolution (10,000 years). Throughout recorded history, and in many cultures, the cannabis plant has been grown as a source of food (hemp seeds) and textiles. As an herbal medicine, cannabis was used to treat an extensive list of health problems, from chronic pain to skin infections. While our ancestors did not understand how or why cannabis alleviated their symptoms, they continued to rely on products made from cannabis plants. Hemp plants were used for many purposes. Humans used hemp fibers for making rope and fabrics, seeds for nutrition, and flowers for herbal medicine.
Over time, humans began to understand that different cultivars of cannabis could be specialized for these different purposes. Hemp plants tended to be tall, thin, and lanky, producing seeds. On the other hand, marijuana plants were identified as short, stocky, and flowering. These plants were grown separately and eventually specialized into what we know today as hemp and marijuana, respectively.
In 2737 BC, the Pen Ts’ao Ching reported that the Chinese emperor Shen-Nung used hemp oil as a topical treatment for skin rashes and irritation. Over time, the hemp plant and its many uses found its way all over the world. Hemp traveled to Europe and was used to make clothing and building materials. In Africa, the plant was given to pregnant women before childbirth. Queen Victoria’s doctor, J.R. Reynolds, prescribed CBD-rich cannabis to treat her severe menstrual cramps. Around this time, the well-known physician William Brooke O’Shaughnessy reported that hemp could treat tetanus, epilepsy, rheumatism, and rabies.
Over the next several decades, specifically in the United States, marijuana was bred to become more psychoactive, with cultivators focusing on growing plants rich in THC. In the 1980s, President Ronald Reagan allocated tens of millions of dollars to prove that marijuana causes brain damage. These studies proved the opposite, marijuana does not cause brain damage. This conclusion prompted the Reagan administration to subsidize a series of studies that led to the discovery of the endocannabinoid system.
Today, scientists are interested in the potential benefits of cannabinoids like THC and CBD. The culture around cannabinoids is shifting, and the market for CBD is thought to grow 700% by 2020.
While the study of the endocannabinoid system is still in its infancy, we have come a long way in our understanding. Today, we understand that the endocannabinoid system is a network of receptors and messengers that create the communication system between your body and your brain. It’s like a system of locks and keys.
You have receptors throughout your body (CB1 and CB2), these are the locks. Cannabinoids function as the keys that create a response when the lock is activated. Your body makes two cannabinoids; they are called endocannabinoids because they are created within. Your endocannabinoids are 2- AG and anandamide. Your endocannabinoid system is now known to be responsible for regulating many important biological functions, including:
Ideally, your endocannabinoid system would remain in balance. Unfortunately, under the assault of stress, illness or injury, your body may not produce enough endocannabinoids to fulfill communication requirements. The system becomes unbalanced, communication deteriorates. Some scientists are leaning towards the belief that many diseases and medical condition, are potentially caused by endocannabinoid deficiencies.
CBD oil is an exogenous cannabinoid, that means that it comes from a source outside of your body, the cannabis plant. CBD extracted from the cannabis plant marijuana also contains THC, the cannabinoid responsible for the psychogenic effects of marijuana.
CBD extracted from the cannabis plant hemp only contains trace amounts of THC (<.03 percent), not enough of the cannabinoid to elicit any form of intoxication, thus avoiding the feeling of being “high”. The exogenous cannabinoids of both cannabis plants have the ability to supplement and restore balance to your endocannabinoid system. Some cannabinoids, such as THC, stimulate the endocannabinoid system by binding directly to CB1 or CB2 receptors. CBD, on the other hand, has an indirect effect on the system. An enzyme known as FAAH is responsible for breaking down excess anandamide, a cannabinoid found naturally in the human body. CBD is able to inhibit the enzyme FAAH, which makes it less able to break down anandamide. The exogenous cannabinoids in CBD oil mimic the actions of your naturally occurring cannabinoids, but the effects of exogenous cannabinoids are stronger and longer lasting.
The end result is more anandamide sticks around in neural synapses, lightly activating the endocannabinoid system using the natural compounds found in the human body. Because CBD acts to increase levels of this natural cannabinoid, instead of stimulating the receptors in an “unnatural” or exogenous way, many people believe it can help restore balance to the endocannabinoid system.
Tinctures are a form of CBD oil which is specially designed for oral consumption. Typically, a food-grade oil such as MCT (medium chain triglyceride) oil, derived from coconut oil is mixed with the CBD extracted oil and is used as a carrier oil. A carrier oil is used because cannabinoids like CBD are fat-soluble, meaning they dissolve in fat and are stored in fat throughout the body. Consuming CBD with lipids increases the bioavailability of CBD. These tinctures are popular because of their approachable, easy-to-use design where users can simply place drops under the tongue or add the oil to food or beverages to experience the effects.
Preliminary studies show that CBD has the potential to improve many health conditions regulated by the endocannabinoid system. It’s important to note that the evidence supporting the use of CBD to supplement the endocannabinoid system is based on laboratory studies and the testimony of CBD enthusiasts who use hemp-sourced CBD products.
CBD oil is extracted from cannabis much like any other plant essence is extracted. The CBD compound can be extracted from either hemp or marijuana plants. Many producers extract from the stalks and stems of hemp plants, an industrial form of cannabis that’s high in CBD, in order to avoid legal problems from using recreational marijuana strains. While there are several potential extraction methods, there are two that are commonly used. Those methods include:
After extraction, chemists use a technique called chromatography to remove unwanted plant materials from the product. Sometimes, chemists will also extract terpenes and other minor chemical compounds to produce a “full-spectrum” final product.
CBD oil is also usually decarboxylated before packaging, making the CBD oil more bioavailable. Raw cannabinoids contain a carboxylic acid group, which makes it inactive when consumed in its raw form. That’s why you have to smoke or bake marijuana before using it. The same is true for CBD. In order for CBD oil to be useful when taken orally, it has to be decarboxylated first.
One common question for beginners is whether the source (hemp plants or marijuana plants) of the CBD makes a difference in terms of its effects. From the perspective of chemistry, the answer is no, because the compound CBD is the same no matter what the source. However, the plant source may affect the profile of terpenoids and other cannabinoids found in a full-spectrum extract, so it’s worth doing your research before buying a product.
The CBD oil found online is typically sourced from industrial hemp, a form of cannabis which is legal to grow in many parts of the world. CBD can also be sourced from marijuana, a cannabis plant typically grown for its psychoactive properties. Marijuana tends to be more strictly regulated than hemp.
The important thing to understand is that the active chemical compound, CBD, is the same no matter where it’s sourced. Regardless of the source, it is crucial to choose a product that is grown from pesticide-free, non-GMO plants. When selecting a CBD product, also ensure that it has been third-party tested.
Understandably, many people are cautious about dosing CBD oil. Because the product is usually dispensed with a dropper, it can be challenging to find the right dose. In order to find the right dose, you’ll need to understand the strength or potency of your CBD oil product, and the volume of your dropper.
Check the product’s package for an indication in milligrams of how much CBD is present per unit volume. For example, The CBDistillery offers tinctures in 250mg, 500mg, 1000mg, 2500mg, and 5000mg strengths.
One full dropper contains around 1mL of oil, and 1mL contains about 10 drops. Of course, drop size can vary. With a little bit of math, we can calculate that the 1000mg tincture has approximately 66.66mg of CBD in 1 mL, the 500mg tincture has approximately 33.33mg of CBD in 1 mL, and the 250mg tincture has approximately 16.66mg of CBD in 1 mL.
Based on this, you can calculate the amount of CBD in your dose by relating the number of drops per mL and the CBD per mL. To get an idea of the recommended oral dose, it’s a good idea to read the label on the bottle and follow their dosage instructions.
CBD affects everyone differently, which means that dosage is going to be different from person to person. This has to do with genetic differences in our liver enzymes. When using CBD for the first time, it’s important to start low and go slow. This means you should start with a very small dose and wait to see if you feel the effects. You can slowly increase your dose over time until you feel the effects are working well for you. While you cannot overdose on CBD, studies show that more CBD does not actually mean better effects. It’s, therefore, a good idea to find your personal optimal dosage, which may be different from that of other CBD users.
While browsing a selection of available CBD products, you may notice that some products are labeled as full-spectrum CBD and others are created from CBD isolates. Full-spectrum CBD and CBD isolate both have the potential to work effectively with your endocannabinoid system. There are several distinguishing features between these product types.
Full-spectrum CBD oil contains the essence of the original plant in the same ratios provided by the source plant. Besides cannabidiol, there are 113 other cannabinoids in hemp, plus the resin of the cannabis plant contains a host of phytocannabinoids and plant terpenes, unsaturated hydrocarbons, and flavonoids, powerful antioxidants with immune system benefits.
It is believed that a full- spectrum CBD product takes full advantage of what is called the entourage effect. The theory is that the additional cannabinoids, terpenes, and flavonoids of the original plant source, magnify the effects of the others.
These trace amounts of additional cannabinoids found in full-spectrum CBD may help strengthen the potential impact of the product because they are synergistic. This means that the compounds interact creating a result greater than their individual effects. Some of the additional compounds available in full spectrum CBD oil include:
While it may appear that full-spectrum CBD oil should be your product of choice, there are many reasons you may prefer to use a CBD isolate. CBD isolate is essentially a full- spectrum CBD oil that has been “purified.” The plant terpenes are removed, the result is a product that is 99 percent pure CBD. You should know that most of the potential benefits of cannabis are obtained from the cannabidiol. Some of the advantages to selecting CBD isolate include:
CBD oil is a fast-growing industry, and unfortunately, this means there are some unscrupulous companies popping up making false claims about the sources, quality, and purity of their products to try and make a fast buck.
It’s very important to do your research before choosing a source for your CBD oil. You’ll want to make sure the company is transparent about their extraction methods, their sources, and the purity of the product. Make sure to look on a company’s website for 3rd party lab results. If these are not posted and regularly updated, it is recommended that you find a different source of CBD oil and CBD products.
Reviews are also another great source of information, but make sure the company’s reviews look real. If every product is rated 5 stars, or if the reviews all look the same, keep looking. If a company is recommended on a 3rd party website, that’s a good sign.
There are various reasons people may be required to take a drug test. Regardless of the reason, it is important to understand how CBD oil may affect the results of a drug test.
Marijuana drug tests are designed to detect a metabolite of THC known as 11-COOH-THC, or “carboxy THC”. This type of drug test will report a “fail” if the person has ingested THC or potentially other cannabinoids with the previous two weeks.
Because some CBD oil products may contain trace amounts of THC, ingesting a full spectrum CBD oil may result in testing positive for THC. If you are regularly drug tested, it is a much safer bet to use a 99.9% pure product CBD oil which has a far less chance of being detected in a drug test since drug tests do not test for CBD or its metabolites.
Regardless, if you are at all concerned about failing a drug test, it is recommended that you do not consume any cannabis products.
Our understanding of CBD products has come a long way since hemp appeared to fall out of favor in the 1930s. The signing of Controlled Substance Act of 1970, along with the creation of the Drug Enforcement Administration (DEA) resulted in hemp being grouped with marijuana. While some believe this classification was made in error, it resulted in the inability to grow or cultivate hemp in the United States, although it was legal to import hemp for industrial use.
Fortunately, the laws have since changed. Many of the restrictions placed on industrial hemp were lifted when President Obama signed The US Farm Bill, (the Agricultural Act of 2014). Now it is legal to grow hemp for research and pilot programs. Today hemp (<0.03 percent THC) is legally grown in 19 states, and hemp products are not regulated by the Drug Enforcement Administration, since hemp cannot cause any intoxicating effects.
CBD oil is a popular product that many people are using to increase their general health and wellbeing. CBD has a long history of human use, tracing back for millennia. It’s important to note that CBD products are not intended to treat or cure any medical conditions. CBD is not a drug; it is not a medication. CBD is a dietary supplement with the potential to benefit your endocannabinoid system. Anyone with a chronic health condition or taking medication should discuss their intentions with their healthcare provider before adding any dietary supplements. CBD is known to interact with several medications.
We encourage you to learn all you can about your endocannabinoid system and the potential benefits of CBD supplements. Download The Ultimate User Guide to learn more about CBD extraction and the importance of selecting organic, non-GMO CBD supplements. To experience the potential benefits of CBD oil for yourself, or even your pet, visit CBDistillery and explore our selection of quality CBD oil, isolates, capsules and topical ointments. Learn more about the potential benefits of CBD oil and what CBD could do for you.