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The Truth About CBD Oil Without THC: Does It Work? 

Written By Ellese Symons Apr 10th 2023
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Cannabis researchers have been investigating the effects of CBD and THC for decades. Although hemp-derived products with unaltered cannabinoid concentrations don't cause intoxication, detailed lab reports will show a small amount of THC. Some people are comfortable with non-intoxicating amounts of THC in their CBD oil, others are not. 

While investigating your options, you're sure to find numerous CBD oil products without THC. But you'll also find plenty of comments from people claiming they get their best results from tinctures, topicals, and gummies with their natural CBD-to-THC ratios intact. Does that mean CBD brands are selling products that don't work? Before limiting your options based on the opinion of others (or misinformation), you deserve to know the truth about CBD oil without THC. 

CBD vs THC: Understanding the Differences and Similarities  

Hemp-derived CBD (cannabidiol) and THC (tetrahydrocannabinol) are just two of more than 113 potentially beneficial cannabinoids in the oil extracted from hemp's stalks, stems, and flowers. They have the same molecular composition, 30 hydrogen atoms, 21 carbon atoms, and two oxygen atoms. But there are slight differences in the way those atoms are arranged (Baldwin, 2021). 

The molecular shape of THC allows the cannabinoid to bind with a specific chemical receptor in your brain in a way that produces the type of recreational effects THC-dominant cannabis strains are known for (McPartland & Pruitt, 1999). CBD impacts the same receptor (CB1) but does not activate the CB1 receptor. Instead, it asserts its influence through interaction with multiple molecular targets, including the receptors of the dopamine, GABA, and serotonin systems. CBD also inhibits THC's ability to bind with CB1 (Alger, 2013). 

CBD Without THC: Benefits and Drawbacks 

CBD has considerable health and wellness potential typically credited to the cannabinoid's ability to interact with the largest regulatory system in your body, your endocannabinoid system (ECS) (Petrocellis & Marzo, 2009).The receptor in your brain that THC binds to is part of that system. Based on the feedback of nearly 2000 CBD users in a 2019 CBDistillery® customer survey, most report positive effects using hemp-derived products for better sleep, discomfort after physical activity, relaxation, and more. Cannabis researchers believe CBD helps support ECS function in a way that promotes homeostasis (Sallaberry & Astern). 

Many CBD users choose full spectrum products to take advantage of the way the combined effects of the plant's many cannabinoids and terpenes, including the THC, amplifies the impact of each active component. It's a property cannabis is known for called an "entourage" effect (Nahler et al., 2019). But THC is not essential in terms of CBD's overall health and wellness potential. In a review published in the Journal of Clinical Medical Research, investigators detailing CBD's potential benefits for a specific range of concerns state that most of the data compiled in their study documented the effects of the "pure form" of CBD administered through oral consumption, inhalation, or capsules. (Larsen & Shahinas, 2020). 

What Products Are Best for People Who Prefer CBD Oil Without THC?  

Anyone interested in the health and wellness potential of CBD without THC can choose from a wide range of products made with broad spectrum hemp extract or CBD isolate powder. Broad spectrum CBD oil has many of the same minor cannabinoids and terpenes as full spectrum, but the THC is reduced to non-detectable levels (less than .01%) through a process called chromatography. 

With broad spectrum CBD oil products, you'll still get the potency-maximizing potential of an entourage effect. Some CBD users feel removing the THC diminishes its impact (Wilkins, 2022), others report the effects are nearly identical. Products made with 0% THC CBD isolate have no additional cannabinoids, terpenes, or phytonutrients. All that remains after a process called winterization is a flavorless, odorless, highly potent, crystalline powder that's nearly 100% pure cannabidiol (Griffin, 2019). 

How to Choose CBD Oil Products Without THC 

The quality of the hemp extract used to make any CBD oil product can have a huge impact on your experience.The best CBD manufacturers insist on natural farming practices and rigorous product testing, every batch. Why? To ensure consumer safety. 

Industrial hemp is a hyperaccumulator. Its roots pull heavy metals, pesticides, and microbial contaminants from the soil (Montoya et al., 2020), potency can vary from one crop to the next, and chemical extraction can leave solvent residue behind. 

CBDistillery® products are sourced from naturally farmed crops grown on American soil. We use the best food-safe extraction methods available, and our products are batch-tested, and quality assured. Now that you know you don't need THC to benefit from the health and wellness potential of CBD, you may want to consider which of the following 0% THC products would be the best fit for your daily routine. 

CBDistillery® Broad Spectrum and 0% THC Isolate Tinctures  

CBDistillery® Broad Spectrum CBD Oil Tinctures and 0% THC CBD Isolate Tinctures are made with hemp extract and a carrier oil. You can use your tincture to add CBD to beverages, snacks, or your favorite recipes. For fast-acting results, hold the oil beneath your tongue for 45-60 seconds before swallowing. 

CBDistillery® Broad Spectrum Gummies  

CBDistillery® Broad Spectrum Anytime Gummies are flavorful and delicious. Each hemp supplement gives you a 30mg serving of CBD with an enticing tropical fruit flavor. Our Broad Spectrum CBD Sleep Gummies have a mixed berry flavor and the sleep-promoting potential of 2mg of melatonin per serving.   

CBDistillery® CBD Isolate Topicals  

For fast-acting, targeted relief, consider trying a CBDistillery® CBD Relief Stick. Our regular strength CBD Relief Stick gives you 500 mg of CBD. Our extra strength formula contains 1000 mg of CBD. For non-greasy relief with a soothing aroma, try our CBD Isolate Cooling Cream or CBD Isolate Warming Cream

CBDistillery® Broad Spectrum CBD Softgels  

Softgels are convenient and portable. Great for home use or on the go, each softgel gives you a consistent, pre-measured 30mg serving of CBD encased in a smooth, easy-to-swallow gelatin shell. CBDistillery® Broad Spectrum CBD Softgels are available in 30 and 60-count bottles. 

CBDistillery® CBDelicious CBD Isolate Powder  

CBDistillery® High Purity CBDelicious CBD Isolate Powder is a great way to add 0% THC CBD to your favorite recipes. We suggest adding this light powder to baked goods, candy recipes, shakes, smoothies, soups, or sauces because there's nothing to alter the flavor or aroma of your creations. 

Frequently Asked Questions About CBD Oil Without THC 

How Much CBD Oil Without THC Should I Take?  

You'll find serving size suggestions on every label. However, every CBD user is different. We generally recommend starting with a partial serving. Then increase the amount you're using gradually over time. Ideally, you'll want to use the smallest serving size that gives you positive results. 

Can CBD Oil Without THC Get You High?  

CBD is a non-intoxicating cannabinoid. It doesn't cause the type of euphoria THC-dominant marijuana strains are known for. When you choose CBDistillery® products made with broad spectrum hemp extract or pure CBD isolate powder, the THC levels are non-detectable (.01mg or less).   

Is CBD Without THC Legal?  

Hemp-derived CBD, with or without THC, is legal at the federal level, provided the THC concentrations remain below .03%. Most states allow hemp-derived CBD, but several prohibit cannabis products of any kind (Laurence, 2023). We suggest reviewing the laws in your area before committing to a purchase. 

What Are the Side Effects of CBD Oil Without THC?  

CBD is generally well tolerated and considered safe for most people. The World Health Organization reports "no evidence of public health-related problems" (WHO, 2020). However, CBD can cause dry mouth, fatigue, digestive upset, or changes in appetite (Bergamaschi et al., 2011). Cannabinoids can also interact with prescription and over-the-counter medications. If you have questions or concerns, consult your healthcare provider. 

How Long Does It Take for CBD Without THC to Work?  

It can take up to two hours (or longer) for the CBD in softgels, gummies, or CBD-infused beverages to clear your digestive system. 

But you may not get the relief you expect right away. While you're sure to find numerous comments from people claiming impressive results within hours of their first serving, everyone is different. Most of our survey respondents report achieving their best results within 7-14 days of consistent use. 

Can You Use CBD Oil Without THC for Mild or Temporary Anxiety?  

Every CBD user has a unique physical chemistry. Although you won't know how supporting ECS function with broad spectrum CBD oil or a pure CBD oil tincture will impact your system until you try it, favorable results are possible. Of nearly 2000 respondents in a 2019 customer survey, 89% report that CBD helps calm their minds and, 88% tell us CBD helps with mild or temporary anxiety. 

Is CBD Oil Without THC Addictive?  

Hemp-derived CBD products are not addictive. According to the report published by the World Health Organization (WHO), there are "no reports of abuse or dependence relating to the use of pure CBD." Our survey respondents seem to agree. Of our nearly 2000 participants in a 2019 customer survey using products with and without THC, 98% do not feel addicted.

Could You Benefit from High-Quality CBD Oil Without THC?  

Hemp-derive CBD oil is non-intoxicating and generally well tolerated. Although many people prefer the effects of full spectrum CBD, products with less than 0.3% THC, numerous reports confirm that CBD oil with non-detectable THC levels can also deliver positive results. If you're leaning toward trying CBD oil without THC but not quite sure where to start, consider taking our 3-minute CBD Quiz or scheduling a personal consultation. CBDistillery® products are quality assured, rigorously tested, and backed by a 60-day satisfaction guarantee. 


Alger B, Ph.D. (2013) Getting High on the Endocannabinoid System. 14, Cerebrum. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997295/ 

Baldwin, J. (2021) CBD vs THC: What Are the Differences? Weed News. 

Bergamaschi M, Mateus R, et al. (2011) Safety and Side Effect of Cannabidiol, a Cannabis Sativa Constituent. 6(4) Curr Drug Saf 237-49. https://doi.org/10.2174/157488611798280924 

Griffin, L. (2019) Winterization and Filtration of Cannabis Extracts. Extraction Magazine. 

Larsen C, Shahinas S. (2020) Dosage, Efficacy and Safety of Cannabidiol Administration in Adults: A Systematic Review of Human Trials. 12(3) J Clin Med Res 129-41. 

Laurence, E. (2023) Your Guide to CBD Legalization By State. Forbes Health. 

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Sallaberry C, Astern L. (2018) The Endocannabinoid System, Our Universal Regulator. 34(6) JYI 48-55. https://www.jyi.org/2018-june/2018/6/1/the-endocannabinoid-system-our-universal-regulator 

Wilkins T. (2022) What Is the Entourage Effect? How This Enhances CBD Effects. Marijuana Takers. 

World Health Organization. (2020) Cannabidiol (CBD) Critical Review Report. PDF https://www.who.int/docs/default-source/controlled-substances/whocbdreportmay2018-2.pdf?sfvrsn=f78db177_2